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Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming

Direct conversion of non-neural cells into induced neurons holds great promise for brain repair. As the most common malignant tumor in the central nervous system, glioma is currently incurable due to its exponential growth and invasive behavior. Given that neurons are irreversible postmitotic cells,...

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Detalles Bibliográficos
Autores principales: Cheng, Xueyan, Tan, Zijian, Huang, Xiao, Yuan, Yimin, Qin, Shangyao, Gu, Yakun, Wang, Dan, He, Cheng, Su, Zhida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627512/
https://www.ncbi.nlm.nih.gov/pubmed/31212628
http://dx.doi.org/10.3390/cells8060571