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Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs

Human breast cancer is characterized by a high degree of inter-patients heterogeneity in terms of histology, genomic alterations, gene expression patterns, and metastatic behavior, which deeply influences individual prognosis and treatment response. The main cause of mortality in breast cancer is th...

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Detalles Bibliográficos
Autores principales: Punzi, Simona, Meliksetian, Marine, Riva, Laura, Marocchi, Federica, Pruneri, Giancarlo, Criscitiello, Carmen, Orsi, Franco, Spaggiari, Lorenzo, Casiraghi, Monica, Della Vigna, Paolo, Luzi, Lucilla, Curigliano, Giuseppe, Pelicci, Pier Giuseppe, Lanfrancone, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627522/
https://www.ncbi.nlm.nih.gov/pubmed/31216647
http://dx.doi.org/10.3390/cells8060605