Phenotypic Effects of FGF4 Retrogenes on Intervertebral Disc Disease in Dogs

Two FGF4 retrogenes on chromosomes 12 (12-FGF4RG) and 18 (18-FGF4RG) contribute to short-limbed phenotypes in dogs. 12-FGF4RG has also been associated with intervertebral disc disease (IVDD). Both of these retrogenes were found to be widespread among dog breeds with allele frequencies ranging from 0...

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Detalles Bibliográficos
Autores principales: Batcher, Kevin, Dickinson, Peter, Giuffrida, Michelle, Sturges, Beverly, Vernau, Karen, Knipe, Marguerite, Rasouliha, Sheida Hadji, Drögemüller, Cord, Leeb, Tosso, Maciejczyk, Kimberly, Jenkins, Christopher A., Mellersh, Cathryn, Bannasch, Danika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627552/
https://www.ncbi.nlm.nih.gov/pubmed/31181696
http://dx.doi.org/10.3390/genes10060435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627552/
https://www.ncbi.nlm.nih.gov/pubmed/31181696
http://dx.doi.org/10.3390/genes10060435

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