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Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to standard chemo- and radiotherapy. Recently, a new class of non-platinum-based halogenated molecules (called FMD compounds) was discovered that selectively kills cancer cells. Here, we investigate the potential of 1,2-Diamino-...

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Detalles Bibliográficos
Autores principales: Goetze, Robert G., Buchholz, Soeren M., Ou, Ning, Zhang, Qinrong, Patil, Shilpa, Schirmer, Markus, Singh, Shiv K., Ellenrieder, Volker, Hessmann, Elisabeth, Lu, Qing-Bin, Neesse, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627568/
https://www.ncbi.nlm.nih.gov/pubmed/31181844
http://dx.doi.org/10.3390/cells8060563