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Transcriptome Changes of Skeletal Muscle RNA-Seq Speculates the Mechanism of Postprandial Hyperglycemia in Diabetic Goto-Kakizaki Rats During the Early Stage of T2D

To address how skeletal muscle contributes to postprandial hyperglycemia, we performed skeletal muscle transcriptome analysis of diabetic Goto-Kakizaki (GK) and control Wistar rats by RNA sequencing (RNA-Seq). We obtained 600 and 1785 differentially expressed genes in GK rats compared to those Wista...

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Detalles Bibliográficos
Autores principales: Zhang, Wenlu, Meng, Yuhuan, Fu, Shuying, Li, Xingsong, Chen, Zixi, Huang, Lizhen, Du, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627578/
https://www.ncbi.nlm.nih.gov/pubmed/31141985
http://dx.doi.org/10.3390/genes10060406