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An alternative trial-level measure for evaluating failure-time surrogate endpoints based on prediction error

To validate a failure-time surrogate for an established failure-time clinical endpoint such as overall survival, the meta-analytic approach is commonly used. The standard correlation approach considers two levels: the individual level, with Kendall's τ measuring the rank correlation between the...

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Detalles Bibliográficos
Autores principales: Belhechmi, Shaima, Michiels, Stefan, Paoletti, Xavier, Rotolo, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627581/
https://www.ncbi.nlm.nih.gov/pubmed/31338479
http://dx.doi.org/10.1016/j.conctc.2019.100402