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Novel Stenotic Microchannels to Study Thrombus Formation in Shear Gradients: Influence of Shear Forces and Human Platelet-Related Factors

Thrombus formation in hemostasis or thrombotic disease is initiated by the rapid adhesion, activation, and aggregation of circulating platelets in flowing blood. At arterial or pathological shear rates, for example due to vascular stenosis or circulatory support devices, platelets may be exposed to...

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Detalles Bibliográficos
Autores principales: Lui, Mathew, Gardiner, Elizabeth E., Arthur, Jane F., Pinar, Isaac, Lee, Woei Ming, Ryan, Kris, Carberry, Josie, Andrews, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627598/
https://www.ncbi.nlm.nih.gov/pubmed/31216638
http://dx.doi.org/10.3390/ijms20122967