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Novel Stenotic Microchannels to Study Thrombus Formation in Shear Gradients: Influence of Shear Forces and Human Platelet-Related Factors
Thrombus formation in hemostasis or thrombotic disease is initiated by the rapid adhesion, activation, and aggregation of circulating platelets in flowing blood. At arterial or pathological shear rates, for example due to vascular stenosis or circulatory support devices, platelets may be exposed to...
Autores principales: | Lui, Mathew, Gardiner, Elizabeth E., Arthur, Jane F., Pinar, Isaac, Lee, Woei Ming, Ryan, Kris, Carberry, Josie, Andrews, Robert K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627598/ https://www.ncbi.nlm.nih.gov/pubmed/31216638 http://dx.doi.org/10.3390/ijms20122967 |
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