Functional Interaction of Hypoxia-Inducible Factor 2-Alpha and Autophagy Mediates Drug Resistance in Colon Cancer Cells

Hypoxia and the accumulation of hypoxia-inducible factors (HIFs) in tumors have been associated with therapeutic resistance and with autophagy establishment. We examined the effects of stable knockdown of HIF-1α or HIF-2α expression on autophagy and drug resistance in colon cancer cells. We found th...

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Detalles Bibliográficos
Autores principales: Saint-Martin, Abril, Martínez-Ríos, Jacobo, Castañeda-Patlán, M. Cristina, Sarabia-Sánchez, Miguel Angel, Tejeda-Muñoz, Nydia, Chinney-Herrera, Alberto, Soldevila, Gloria, Benelli, Roberto, Santoyo-Ramos, Paula, Poggi, Alessandro, Robles-Flores, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627604/
https://www.ncbi.nlm.nih.gov/pubmed/31151160
http://dx.doi.org/10.3390/cancers11060755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627604/
https://www.ncbi.nlm.nih.gov/pubmed/31151160
http://dx.doi.org/10.3390/cancers11060755

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