Cargando…

Functional Interaction of Hypoxia-Inducible Factor 2-Alpha and Autophagy Mediates Drug Resistance in Colon Cancer Cells

Hypoxia and the accumulation of hypoxia-inducible factors (HIFs) in tumors have been associated with therapeutic resistance and with autophagy establishment. We examined the effects of stable knockdown of HIF-1α or HIF-2α expression on autophagy and drug resistance in colon cancer cells. We found th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saint-Martin, Abril, Martínez-Ríos, Jacobo, Castañeda-Patlán, M. Cristina, Sarabia-Sánchez, Miguel Angel, Tejeda-Muñoz, Nydia, Chinney-Herrera, Alberto, Soldevila, Gloria, Benelli, Roberto, Santoyo-Ramos, Paula, Poggi, Alessandro, Robles-Flores, Martha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627604/ https://www.ncbi.nlm.nih.gov/pubmed/31151160 http://dx.doi.org/10.3390/cancers11060755

Ejemplares similares

Hypoxia-inducible factors, mTOR, and astrin constitute an integrative regulatory network in colon cancer cells
por: Saint-Martin, Abril, et al.
Publicado: (2022)

Hypoxia-Inducible Factors Modulate the Stemness and Malignancy of Colon Cancer Cells by Playing Opposite Roles in Canonical Wnt Signaling
por: Santoyo-Ramos, Paula, et al.
Publicado: (2014)

Canonical Wnt Pathway Is Involved in Chemoresistance and Cell Cycle Arrest Induction in Colon Cancer Cell Line Spheroids
por: Moreno-Londoño, Angela Patricia, et al.
Publicado: (2023)

Protein Kinase C Delta Negatively Modulates Canonical Wnt Pathway and Cell Proliferation in Colon Tumor Cell Lines
por: Hernández-Maqueda, José G., et al.
Publicado: (2013)

Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
por: Wischin, Sabina, et al.
Publicado: (2017)

Signaling Pathways Involved in Nutrient Sensing Control in Cancer Stem Cells: An Overview
por: Robles-Flores, Martha, et al.
Publicado: (2021)

Non-canonical Wnt/Ca2+ signaling is essential to promote self-renewal and proliferation in colon cancer stem cells
por: Sarabia-Sánchez, Miguel Angel, et al.
Publicado: (2023)

O-GlcNAcylation Is Involved in the Regulation of Stem Cell Markers Expression in Colon Cancer Cells
por: Fuentes-García, Gabriela, et al.
Publicado: (2019)

Glosas martianas /
por: Sarabia, Nydia, 1922-
Publicado: (2002)

Overexpression of Multifunctional Protein p32 Promotes a Malignant Phenotype in Colorectal Cancer Cells
por: Egusquiza-Alvarez, Carlos Alejandro, et al.
Publicado: (2021)

Topological data analysis of antibody dynamics of severe and non-severe patients with COVID-19
por: Blanco-Rodríguez, Rodolfo, et al.
Publicado: (2023)

Lysosomes are required for early dorsal signaling in the Xenopus embryo
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor-1 Alpha Pathway in Non-Small Cell Lung Cancer Cells
por: Hsu, Han-Lin, et al.
Publicado: (2019)

miRNA-411 Regulates Chondrocyte Autophagy in Osteoarthritis by Targeting Hypoxia-Inducible Factor 1 alpha (HIF-1α)
por: Yang, Fei, et al.
Publicado: (2020)

The Study of Expression of Hypoxia-Inducible Factor-1 Alpha (HIF-1 Alpha) and Hypoxia-Inducible Factor-2 Alpha (HIF-2 Alpha) in Oral Squamous Cell Carcinoma: An Immunohistochemical Study
por: Mahapatra, Niva, et al.
Publicado: (2023)

Editorial: Tumor Cell Metabolism and Autophagy as Therapeutic Targets
por: Jacobo-Herrera, Nadia, et al.
Publicado: (2020)

Hypoxia, MTOR and autophagy: Converging on senescence or quiescence
por: Blagosklonny, Mikhail V.
Publicado: (2013)

Hypoxia and Selective Autophagy in Cancer Development and Therapy
por: Daskalaki, Ioanna, et al.
Publicado: (2018)

Protocol for culturing and imaging of ectodermal cells from Xenopus
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha
por: Zhang, Chao, et al.
Publicado: (2017)

Targeting Membrane Trafficking as a Strategy for Cancer Treatment
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Hypoxia Shapes Autophagy in LPS-Activated Dendritic Cells
por: Monaci, Sara, et al.
Publicado: (2020)

Differences in the Autophagy Response to Hypoxia in the Hippocampus and Neocortex of Rats
por: Churilova, Anna, et al.
Publicado: (2022)

Nanoproteomic Approach for Isolation and Identification of Potential Biomarkers in Human Urine from Adults with Normal Weight, Overweight and Obesity
por: Hernandez-Leon, Sergio G., et al.
Publicado: (2021)

Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism
por: GUI, LAN, et al.
Publicado: (2016)

Hyperbaric Oxygen Improves Cerebral Ischemia/Reperfusion Injury in Rats Probably via Inhibition of Autophagy Triggered by the Downregulation of Hypoxia-Inducing Factor-1 Alpha
por: Wang, Cuiting, et al.
Publicado: (2021)

Inter-Alpha Inhibitor Proteins Modify the Microvasculature after Exposure to Hypoxia–Ischemia and Hypoxia in Neonatal Rats
por: Girolamo, Francesco, et al.
Publicado: (2023)

The role of hypoxia-inducible factor-1 alpha in TEMPI syndrome
por: Khan, Sujoy
Publicado: (2011)

Postexercise urinary alpha-1 acid glycoprotein is not dependent on hypoxia
por: Joyce, Kelsey E., et al.
Publicado: (2022)

The Role of Hypoxia-Inducible Factor-1 Alpha in Renal Disease
por: Liu, Huixia, et al.
Publicado: (2022)

Alpha Particles Induce Autophagy in Multiple Myeloma Cells
por: Gorin, Jean-Baptiste, et al.
Publicado: (2015)

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia
por: Li, Q, et al.
Publicado: (2010)

Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress
por: Lu, Qing, et al.
Publicado: (2015)

Baicalin attenuates liver hypoxia/reoxygenation injury by inducing autophagy
por: Liu, Feng, et al.
Publicado: (2018)

Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance
por: Feng, Helin, et al.
Publicado: (2016)

Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia
por: Yu, Ping, et al.
Publicado: (2021)

Esomeprazole inhibits hypoxia/endothelial dysfunction–induced autophagy in preeclampsia
por: Gu, Shengyi, et al.
Publicado: (2022)

Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival
por: Zaarour, Rania F., et al.
Publicado: (2021)

The effect of hypoxia-inducible factor 1-alpha on hypoxia-induced apoptosis in primary neonatal rat ventricular myocytes
por: Zhou, Yan-Fang, et al.
Publicado: (2010)

Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor
por: Renfrow, Jaclyn J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_utjg318tms2fgp8c0i55m6jd1m