Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads

Culture systems for three-dimensional tissues, such as multicellular spheroids, are indispensable for high-throughput screening of primary or patient-derived xenograft (PDX)-expanded cancer tissues. Oxygen supply to the center of such spheroids is particularly critical for maintaining cellular funct...

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Detalles Bibliográficos
Autores principales: Mihara, Hirotaka, Kugawa, Mai, Sayo, Kanae, Tao, Fumiya, Shinohara, Marie, Nishikawa, Masaki, Sakai, Yasuyuki, Akama, Takeshi, Kojima, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627619/
https://www.ncbi.nlm.nih.gov/pubmed/31159231
http://dx.doi.org/10.3390/cells8060525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627619/
https://www.ncbi.nlm.nih.gov/pubmed/31159231
http://dx.doi.org/10.3390/cells8060525

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