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Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads

Culture systems for three-dimensional tissues, such as multicellular spheroids, are indispensable for high-throughput screening of primary or patient-derived xenograft (PDX)-expanded cancer tissues. Oxygen supply to the center of such spheroids is particularly critical for maintaining cellular funct...

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Detalles Bibliográficos
Autores principales:	Mihara, Hirotaka, Kugawa, Mai, Sayo, Kanae, Tao, Fumiya, Shinohara, Marie, Nishikawa, Masaki, Sakai, Yasuyuki, Akama, Takeshi, Kojima, Nobuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627619/ https://www.ncbi.nlm.nih.gov/pubmed/31159231 http://dx.doi.org/10.3390/cells8060525

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