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Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer

DUSP6 is a dual-specificity phosphatase (DUSP) involved in breast cancer progression, recurrence, and metastasis. DUSP6 is predominantly cytoplasmic in HER2+ primary breast cancer cells, but the expression and subcellular localization of DUSPs, especially DUSP6, in HER2-positive circulating tumor ce...

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Detalles Bibliográficos
Autores principales: Wu, Fan, McCuaig, Robert D., Sutton, Christopher R., Tan, Abel H. Y., Jeelall, Yoshni, Bean, Elaine G., Dai, Jin, Prasanna, Thiru, Batham, Jacob, Malik, Laeeq, Yip, Desmond, Dahlstrom, Jane E., Rao, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627630/
https://www.ncbi.nlm.nih.gov/pubmed/31238530
http://dx.doi.org/10.3390/ijms20123080