Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors

A greater understanding of the hypersensitivity and curability of testicular germ cell tumors (TGCTs) has the potential to inform strategies to sensitize other solid tumors to conventional chemotherapies. The mechanisms of cisplatin hypersensitivity and resistance in embryonal carcinoma (EC), the st...

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Detalles Bibliográficos
Autores principales: Singh, Ratnakar, Fazal, Zeeshan, Corbet, Andrea K., Bikorimana, Emmanuel, Rodriguez, Jennifer C., Khan, Ema M., Shahid, Khadeeja, Freemantle, Sarah J., Spinella, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627640/
https://www.ncbi.nlm.nih.gov/pubmed/31181810
http://dx.doi.org/10.3390/cancers11060796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627640/
https://www.ncbi.nlm.nih.gov/pubmed/31181810
http://dx.doi.org/10.3390/cancers11060796

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