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The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

Most patients with pancreatic ductal adenocarcinoma (PDAC) undergoing curative resection relapse within months, often with liver metastases. The hepatic microenvironment determines induction and reversal of dormancy during metastasis. Both tumor growth and metastasis depend on the Tumor necrosis fac...

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Detalles Bibliográficos
Autores principales: Miarka, Lauritz, Hauser, Charlotte, Helm, Ole, Holdhof, Dörthe, Beckinger, Silje, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Lenk, Lennart, Rahn, Sascha, Mikulits, Wolfgang, Trauzold, Anna, Sebens, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627672/
https://www.ncbi.nlm.nih.gov/pubmed/31146405
http://dx.doi.org/10.3390/cancers11060745