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The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
Most patients with pancreatic ductal adenocarcinoma (PDAC) undergoing curative resection relapse within months, often with liver metastases. The hepatic microenvironment determines induction and reversal of dormancy during metastasis. Both tumor growth and metastasis depend on the Tumor necrosis fac...
Autores principales: | Miarka, Lauritz, Hauser, Charlotte, Helm, Ole, Holdhof, Dörthe, Beckinger, Silje, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Lenk, Lennart, Rahn, Sascha, Mikulits, Wolfgang, Trauzold, Anna, Sebens, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627672/ https://www.ncbi.nlm.nih.gov/pubmed/31146405 http://dx.doi.org/10.3390/cancers11060745 |
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