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Analysis of the TP53 Deleterious Single Nucleotide Polymorphisms Impact on Estrogen Receptor Alpha-p53 Interaction: A Machine Learning Approach

Breast cancer is a leading cancer type and one of the major health issues faced by women around the world. Some of its major risk factors include body mass index, hormone replacement therapy, family history and germline mutations. Of these risk factors, estrogen levels play a crucial role. Among the...

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Detalles Bibliográficos
Autores principales: Chitrala, Kumaraswamy Naidu, Nagarkatti, Mitzi, Nagarkatti, Prakash, Yeguvapalli, Suneetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627686/
https://www.ncbi.nlm.nih.gov/pubmed/31216622
http://dx.doi.org/10.3390/ijms20122962