PARP Inhibitors in Ovarian Cancer: The Route to “Ithaca”

Poly (ADP-ribose) polymerase (PARP) inhibitors are a novel class of therapeutic agents that target tumors with deficiencies in the homologous recombination DNA repair pathway. Genomic instability characterizes high-grade serous ovarian cancer (HGSOC), with one half of all tumors displaying defects i...

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Detalles Bibliográficos
Autores principales: Boussios, Stergios, Karathanasi, Afroditi, Cooke, Deirdre, Neille, Cherie, Sadauskaite, Agne, Moschetta, Michele, Zakynthinakis-Kyriakou, Nikolaos, Pavlidis, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627688/
https://www.ncbi.nlm.nih.gov/pubmed/31109041
http://dx.doi.org/10.3390/diagnostics9020055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627688/
https://www.ncbi.nlm.nih.gov/pubmed/31109041
http://dx.doi.org/10.3390/diagnostics9020055

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