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Low VDAC1 Expression Is Associated with an Aggressive Phenotype and Reduced Overall Patient Survival in Cholangiocellular Carcinoma

Cancer cells frequently exhibit dysfunctional oxidative phosphorylation (OXPHOS) and a concomitant increase in glycolytic flux. We investigated the expression of OXPHOS complex subunits and mitochondrial mass in 34 human cholangiocellular carcinomas (CCCs) and adjacent normal tissue by using tissue...

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Detalles Bibliográficos
Autores principales: Feichtinger, René Günther, Neureiter, Daniel, Kemmerling, Ralf, Mayr, Johannes Adalbert, Kiesslich, Tobias, Kofler, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627691/
https://www.ncbi.nlm.nih.gov/pubmed/31167495
http://dx.doi.org/10.3390/cells8060539