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A (3D-Nuclear) Space Odyssey: Making Sense of Hi-C Maps

Three-dimensional (3D)-chromatin organization is critical for proper enhancer-promoter communication and, therefore, for a precise execution of the transcriptional programs governing cellular processes. The emergence of Chromosome Conformation Capture (3C) methods, in particular Hi-C, has allowed th...

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Detalles Bibliográficos
Autores principales: Mota-Gómez, Irene, Lupiáñez, Darío G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627722/
https://www.ncbi.nlm.nih.gov/pubmed/31146487
http://dx.doi.org/10.3390/genes10060415