Diabetic Pregnancy and Maternal High-Fat Diet Impair Mitochondrial Dynamism in the Developing Fetal Rat Heart by Sex-Specific Mechanisms

Infants born to diabetic or obese mothers are at greater risk of heart disease at birth and throughout life, but prevention is hindered because underlying mechanisms remain poorly understood. Using a rat model, we showed that prenatal exposure to maternal diabetes and a high-fat diet caused diastoli...

Descripción completa

Detalles Bibliográficos
Autores principales: Larsen, Tricia D., Sabey, Kyle H., Knutson, Alexis J., Gandy, Tyler C. T., Louwagie, Eli J., Lauterboeck, Lothar, Mdaki, Kennedy S., Baack, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627740/
https://www.ncbi.nlm.nih.gov/pubmed/31242551
http://dx.doi.org/10.3390/ijms20123090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627740/
https://www.ncbi.nlm.nih.gov/pubmed/31242551
http://dx.doi.org/10.3390/ijms20123090

Ejemplares similares