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An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway

In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor γ (PPAR-γ) ligand 15-deoxy-∆(12,14)-prostaglandin J(2) (15d-PGJ(2)), exerted significant PPAR-γ transc...

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Detalles Bibliográficos
Autores principales: Ju, Zhiran, Su, Mingzhi, Li, Dandan, Hong, Jongki, Im, Dong-Soon, Kim, Suhkmann, Kim, Eun La, Jung, Jee H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627743/
https://www.ncbi.nlm.nih.gov/pubmed/31151271
http://dx.doi.org/10.3390/md17060321