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An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway
In our previous study, a synthetic compound, (+)-(R,E)-6a1, that incorporated the key structures of anti-inflammatory algal metabolites and the endogenous peroxisome proliferator-activated receptor γ (PPAR-γ) ligand 15-deoxy-∆(12,14)-prostaglandin J(2) (15d-PGJ(2)), exerted significant PPAR-γ transc...
Autores principales: | Ju, Zhiran, Su, Mingzhi, Li, Dandan, Hong, Jongki, Im, Dong-Soon, Kim, Suhkmann, Kim, Eun La, Jung, Jee H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627743/ https://www.ncbi.nlm.nih.gov/pubmed/31151271 http://dx.doi.org/10.3390/md17060321 |
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