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Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants

A growing body of evidence indicates that miRNAs may either drive or suppress oncogenesis. However, little is known about somatic mutations in miRNA genes. To determine the frequency and potential consequences of miRNA gene mutations, we analyzed whole exome sequencing datasets of 569 lung adenocarc...

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Detalles Bibliográficos
Autores principales: Galka-Marciniak, Paulina, Urbanek-Trzeciak, Martyna Olga, Nawrocka, Paulina Maria, Dutkiewicz, Agata, Giefing, Maciej, Lewandowska, Marzena Anna, Kozlowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627760/
https://www.ncbi.nlm.nih.gov/pubmed/31181801
http://dx.doi.org/10.3390/cancers11060793