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Rational Design of Alginate Lyase from Microbulbifer sp. Q7 to Improve Thermal Stability

Alginate lyase degrades alginate by the β-elimination mechanism to produce oligosaccharides with special bioactivities. The low thermal stability of alginate lyase limits its industrial application. In this study, introducing the disulfide bonds while using the rational design methodology enhanced t...

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Detalles Bibliográficos
Autores principales: Yang, Min, Yang, Su-Xiao, Liu, Zhe-Min, Li, Nan-Nan, Li, Li, Mou, Hai-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627800/
https://www.ncbi.nlm.nih.gov/pubmed/31242622
http://dx.doi.org/10.3390/md17060378