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Strategies to Overcome Resistance Mechanisms in T-Cell Acute Lymphoblastic Leukemia

Chemoresistance is a major cause of recurrence and death from T-cell acute lymphoblastic leukemia (T-ALL), both in adult and pediatric patients. In the majority of cases, drug-resistant disease is treated by selecting a combination of other drugs, without understanding the molecular mechanisms by wh...

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Detalles Bibliográficos
Autores principales: Follini, Elena, Marchesini, Matteo, Roti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627878/
https://www.ncbi.nlm.nih.gov/pubmed/31226848
http://dx.doi.org/10.3390/ijms20123021