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Dissecting the Prognostic Significance and Functional Role of Progranulin in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is known for its strong dependency on the tumor microenvironment. We found progranulin (GRN), a protein that has been linked to inflammation and cancer, to be upregulated in the serum of CLL patients compared to healthy controls, and increased GRN levels to be asso...

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Detalles Bibliográficos
Autores principales: Schulze-Edinghausen, Lena, Dürr, Claudia, Öztürk, Selcen, Zucknick, Manuela, Benner, Axel, Kalter, Verena, Ohl, Sibylle, Close, Viola, Wuchter, Patrick, Stilgenbauer, Stephan, Lichter, Peter, Seiffert, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627891/
https://www.ncbi.nlm.nih.gov/pubmed/31200555
http://dx.doi.org/10.3390/cancers11060822