Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase

Williams-Beuren syndrome (WBS) is caused by microdeletions of 28 genes and is characterized by cognitive disorder and hypotrophic corpus callosum (CC). Nsun5 gene, which encodes cytosine-5 RNA methyltransferase, is located in the deletion loci of WBS. We have reported that single-gene knockout of Ns...

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Detalles Bibliográficos
Autores principales: Yuan, Zihao, Chen, Peipei, Zhang, Tingting, Shen, Bin, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627898/
https://www.ncbi.nlm.nih.gov/pubmed/31174389
http://dx.doi.org/10.3390/cells8060552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627898/
https://www.ncbi.nlm.nih.gov/pubmed/31174389
http://dx.doi.org/10.3390/cells8060552

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