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Improving the Brain Delivery of Chemotherapeutic Drugs in Childhood Brain Tumors

The central nervous system (CNS) may be considered as a sanctuary site, protected from systemic chemotherapy by the meninges, the cerebrospinal fluid (CSF) and the blood-brain barrier (BBB). Consequently, parenchymal and CSF exposure of most antineoplastic agents following intravenous (IV) administr...

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Detalles Bibliográficos
Autores principales: Triarico, Silvia, Maurizi, Palma, Mastrangelo, Stefano, Attinà, Giorgio, Capozza, Michele Antonio, Ruggiero, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627959/
https://www.ncbi.nlm.nih.gov/pubmed/31200562
http://dx.doi.org/10.3390/cancers11060824