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Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors

Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases expressed on the cell membrane that play crucial roles in both developmental and adult cells. Dysregulation of FGFRs has been implicated in a wide variety of cancers, such as urothelial carcinoma, hepatocellular car...

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Detalles Bibliográficos
Autores principales: Dai, Shuyan, Zhou, Zhan, Chen, Zhuchu, Xu, Guangyu, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627960/
https://www.ncbi.nlm.nih.gov/pubmed/31216761
http://dx.doi.org/10.3390/cells8060614