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Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour

While intratumour genetic heterogeneity of primary clear cell renal cell carcinoma (ccRCC) is well characterized, the genomic profiles of metastatic ccRCCs are seldom studied. We profiled the genomes and transcriptomes of a primary tumour and matched metastases to better understand the evolutionary...

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Detalles Bibliográficos
Autores principales: Ferronika, Paranita, Hof, Joost, Kats-Ugurlu, Gursah, Sijmons, Rolf H., Terpstra, Martijn M., de Lange, Kim, Leliveld-Kors, Annemarie, Westers, Helga, Kok, Klaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628027/
https://www.ncbi.nlm.nih.gov/pubmed/31212796
http://dx.doi.org/10.3390/cancers11060812