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The Hunt for Degrons of the 26S Proteasome

Since the discovery of ubiquitin conjugation as a cellular mechanism that triggers proteasomal degradation, the mode of substrate recognition by the ubiquitin-ligation system has been the holy grail of research in the field. This entails the discovery of recognition determinants within protein subst...

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Detalles Bibliográficos
Autores principales: Ella, Hadar, Reiss, Yuval, Ravid, Tommer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628059/
https://www.ncbi.nlm.nih.gov/pubmed/31200568
http://dx.doi.org/10.3390/biom9060230