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Illegitimate and Repeated Genomic Integration of Cell-Free Chromatin in the Aetiology of Somatic Mosaicism, Ageing, Chronic Diseases and Cancer

Emerging evidence suggests that an individual is a complex mosaic of genetically divergent cells. Post-zygotic genomes of the same individual can differ from one another in the form of single nucleotide variations, copy number variations, insertions, deletions, inversions, translocations, other stru...

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Detalles Bibliográficos
Autores principales: V. Raghuram, Gorantla, Chaudhary, Shahid, Johari, Shweta, Mittra, Indraneel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628102/
https://www.ncbi.nlm.nih.gov/pubmed/31142004
http://dx.doi.org/10.3390/genes10060407