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Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway

Background: Colorectal cancer (CRC) is one of the most prevalent gastrointestinal malignancies. The incidence of CRC has been rapidly increasing in China. Transferrin receptor 1 (TfR1) is a key regulator of cellular iron homeostasis. Several studies have demonstrated TfR1 overexpression in a variety...

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Detalles Bibliográficos
Autores principales: Cui, Can, Cheng, Xiaojing, Yan, Liang, Ding, Huirong, Guan, Xiaoya, Zhang, Wenlong, Tian, Xiuyun, Hao, Chunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628123/
https://www.ncbi.nlm.nih.gov/pubmed/31372038
http://dx.doi.org/10.2147/CMAR.S198911