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Affinity Isolation and Mass Spectrometry Identification of Prostacyclin Synthase (PTGIS) Subinteractome

Prostacyclin synthase (PTGIS; EC 5.3.99.4) catalyzes isomerization of prostaglandin H(2) to prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. At present, limited data exist on functional coupling and possible ways of regulating PTGIS due to insufficient information about prot...

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Detalles Bibliográficos
Autores principales: Ershov, Pavel V., Mezentsev, Yuri V., Kopylov, Arthur T., Yablokov, Evgeniy O., Svirid, Andrey V., Lushchyk, Aliaksandr Ya., Kaluzhskiy, Leonid A., Gilep, Andrei A., Usanov, Sergey A., Medvedev, Alexey E., Ivanov, Alexis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628129/
https://www.ncbi.nlm.nih.gov/pubmed/31226805
http://dx.doi.org/10.3390/biology8020049