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Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. Tumor-derived extracellular vesicles (EVs) induce pre-metastatic niche formation to promote metastasis. We isolated EVs from a highly-metastatic pancreatic cancer cell line and patient-derived primary cancer cells by ult...

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Detalles Bibliográficos
Autores principales: Zhao, Jiangang, Schlößer, Hans A., Wang, Zhefang, Qin, Jie, Li, Jiahui, Popp, Felix, Popp, Marie Christine, Alakus, Hakan, Chon, Seung-Hun, Hansen, Hinrich P., Neiss, Wolfram F., Jauch, Karl-Walter, Bruns, Christiane J., Zhao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628179/
https://www.ncbi.nlm.nih.gov/pubmed/31234517
http://dx.doi.org/10.3390/cancers11060874