Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform

Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for...

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Detalles Bibliográficos
Autores principales: Robinson, Sarah M., Shen, Zuliang, Askim, Jon R., Montgomery, Christopher B., Sintim, Herman O., Semancik, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628196/
https://www.ncbi.nlm.nih.gov/pubmed/31013753
http://dx.doi.org/10.3390/bios9020054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628196/
https://www.ncbi.nlm.nih.gov/pubmed/31013753
http://dx.doi.org/10.3390/bios9020054

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