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Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform
Development of technologies for rapid screening of DNA secondary structure thermal stability and the effects on stability for binding of small molecule drugs is important to the drug discovery process. In this report, we describe the capabilities of an electrochemical, microdevice-based approach for...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628196/ https://www.ncbi.nlm.nih.gov/pubmed/31013753 http://dx.doi.org/10.3390/bios9020054 |