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Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease

Intrastriatal administration of mesenchymal stem cells (MSCs) has shown beneficial effects in rodent models of Huntington disease (HD). However, the invasive nature of surgical procedure and its potential to trigger the host immune response may limit its clinical use. Hence, we sought to evaluate th...

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Detalles Bibliográficos
Autores principales: Yu-Taeger, Libo, Stricker-Shaver, Janice, Arnold, Katrin, Bambynek-Dziuk, Patrycja, Novati, Arianna, Singer, Elisabeth, Lourhmati, Ali, Fabian, Claire, Magg, Janine, Riess, Olaf, Schwab, Matthias, Stolzing, Alexandra, Danielyan, Lusine, Nguyen, Hoa Huu Phuc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628278/
https://www.ncbi.nlm.nih.gov/pubmed/31208073
http://dx.doi.org/10.3390/cells8060595