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Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease
Intrastriatal administration of mesenchymal stem cells (MSCs) has shown beneficial effects in rodent models of Huntington disease (HD). However, the invasive nature of surgical procedure and its potential to trigger the host immune response may limit its clinical use. Hence, we sought to evaluate th...
Autores principales: | Yu-Taeger, Libo, Stricker-Shaver, Janice, Arnold, Katrin, Bambynek-Dziuk, Patrycja, Novati, Arianna, Singer, Elisabeth, Lourhmati, Ali, Fabian, Claire, Magg, Janine, Riess, Olaf, Schwab, Matthias, Stolzing, Alexandra, Danielyan, Lusine, Nguyen, Hoa Huu Phuc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628278/ https://www.ncbi.nlm.nih.gov/pubmed/31208073 http://dx.doi.org/10.3390/cells8060595 |
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