Cargando…

An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress

Emerin is a nuclear envelope protein that contributes to genome organization and cell mechanics. Through its N-terminal LAP2-emerin-MAN1 (LEM)-domain, emerin interacts with the DNA-binding protein barrier-to-autointegration (BAF). Emerin also binds to members of the linker of the nucleoskeleton and...

Descripción completa

Detalles Bibliográficos
Autores principales: Essawy, Nada, Samson, Camille, Petitalot, Ambre, Moog, Sophie, Bigot, Anne, Herrada, Isaline, Marcelot, Agathe, Arteni, Ana-Andreea, Coirault, Catherine, Zinn-Justin, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628311/
https://www.ncbi.nlm.nih.gov/pubmed/31185657
http://dx.doi.org/10.3390/cells8060570