5′,8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance

Purine 5′,8-cyclo-2′-deoxynucleosides (cPu) are tandem-type lesions observed among the DNA purine modifications and identified in mammalian cellular DNA in vivo. These lesions can be present in two diasteroisomeric forms, 5′R and 5′S, for each 2′-deoxyadenosine and 2′-deoxyguanosine moiety. They are...

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Detalles Bibliográficos
Autores principales: Chatgilialoglu, Chryssostomos, Ferreri, Carla, Geacintov, Nicholas E., Krokidis, Marios G., Liu, Yuan, Masi, Annalisa, Shafirovich, Vladimir, Terzidis, Michael A., Tsegay, Pawlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628319/
https://www.ncbi.nlm.nih.gov/pubmed/31141888
http://dx.doi.org/10.3390/cells8060513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628319/
https://www.ncbi.nlm.nih.gov/pubmed/31141888
http://dx.doi.org/10.3390/cells8060513

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