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Amelioration of Behavioral Impairments and Neuropathology by Antiepileptic Drug Topiramate in a Transgenic Alzheimer’s Disease Model Mice, APP/PS1

Alzheimer’s disease (AD) is a neurodegenerative disease that is the main cause of dementia in the elderly. The aggregation of β-amyloid peptides is one of the characterizing pathological changes of AD. Topiramate is an antiepileptic drug, which in addition, is used in the treatment of many neuropsyc...

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Detalles Bibliográficos
Autores principales: Owona, Brice Ayissi, Zug, Caroline, Schluesener, Hermann J., Zhang, Zhi-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628361/
https://www.ncbi.nlm.nih.gov/pubmed/31248209
http://dx.doi.org/10.3390/ijms20123003