Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling

Myeloid phagocytes have evolved to rapidly recognize invading pathogens and clear them through opsonophagocytic killing. The adenylate cyclase toxin (CyaA) of Bordetella pertussis and the edema toxin (ET) of Bacillus anthracis are both calmodulin-activated toxins with adenylyl cyclase activity that...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasan, Shakir, Rahman, Waheed Ur, Sebo, Peter, Osicka, Radim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628411/
https://www.ncbi.nlm.nih.gov/pubmed/31226835
http://dx.doi.org/10.3390/toxins11060362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628411/
https://www.ncbi.nlm.nih.gov/pubmed/31226835
http://dx.doi.org/10.3390/toxins11060362

Ejemplares similares