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Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?

Pore-forming toxins (PFTs) form nanoscale pores across target membranes causing cell death. The pore-forming cytolysins of the RTX (repeats in toxin) family belong to a steadily increasing family of proteins characterized by having in their primary sequences a number of glycine- and aspartate-rich n...

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Detalles Bibliográficos
Autores principales: Ostolaza, Helena, González-Bullón, David, Uribe, Kepa B., Martín, Cesar, Amuategi, Jone, Fernandez-Martínez, Xabier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628442/
https://www.ncbi.nlm.nih.gov/pubmed/31216745
http://dx.doi.org/10.3390/toxins11060354