The role of mutations associated with familial neurodegenerative disorders on blood–brain barrier function in an iPSC model

BACKGROUND: Blood–brain barrier dysfunction is associated with many late-stage neurodegenerative diseases. An emerging question is whether the mutations associated with neurodegenerative diseases can independently lead to blood–brain barrier (BBB) dysfunction. Studies from patient-derived induced pl...

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Detalles Bibliográficos
Autores principales: Katt, Moriah E., Mayo, Lakyn N., Ellis, Shannon E., Mahairaki, Vasiliki, Rothstein, Jeffrey D., Cheng, Linzhao, Searson, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628493/
https://www.ncbi.nlm.nih.gov/pubmed/31303172
http://dx.doi.org/10.1186/s12987-019-0139-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628493/
https://www.ncbi.nlm.nih.gov/pubmed/31303172
http://dx.doi.org/10.1186/s12987-019-0139-4

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