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The role of mutations associated with familial neurodegenerative disorders on blood–brain barrier function in an iPSC model
BACKGROUND: Blood–brain barrier dysfunction is associated with many late-stage neurodegenerative diseases. An emerging question is whether the mutations associated with neurodegenerative diseases can independently lead to blood–brain barrier (BBB) dysfunction. Studies from patient-derived induced pl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628493/ https://www.ncbi.nlm.nih.gov/pubmed/31303172 http://dx.doi.org/10.1186/s12987-019-0139-4 |