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Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy
Cerebral dopamine neurotrophic factor (CDNF) shows beneficial effects in rodent models of Parkinson’s and Alzheimer’s disease. The brain is a challenging target for protein therapy due to its exclusive blood–brain barrier. Hence, the therapeutic protein should be delivered directly to the brain pare...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628564/ https://www.ncbi.nlm.nih.gov/pubmed/30841717 http://dx.doi.org/10.1177/0963689719827943 |