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Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

Cerebral dopamine neurotrophic factor (CDNF) shows beneficial effects in rodent models of Parkinson’s and Alzheimer’s disease. The brain is a challenging target for protein therapy due to its exclusive blood–brain barrier. Hence, the therapeutic protein should be delivered directly to the brain pare...

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Detalles Bibliográficos
Autores principales:	Galli, Emilia, Lindholm, Päivi, Kontturi, Leena-Stiina, Saarma, Mart, Urtti, Arto, Yliperttula, Marjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628564/ https://www.ncbi.nlm.nih.gov/pubmed/30841717 http://dx.doi.org/10.1177/0963689719827943

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