Mechanisms Underlying Spontaneous Action Potential Generation Induced by Catecholamine in Pulmonary Vein Cardiomyocytes: A Simulation Study

Cardiomyocytes and myocardial sleeves dissociated from pulmonary veins (PVs) potentially generate ectopic automaticity in response to noradrenaline (NA), and thereby trigger atrial fibrillation. We developed a mathematical model of rat PV cardiomyocytes (PVC) based on experimental data that incorpor...

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Detalles Bibliográficos
Autores principales: Umehara, Shohei, Tan, Xiaoqiu, Okamoto, Yosuke, Ono, Kyoichi, Noma, Akinori, Amano, Akira, Himeno, Yukiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628582/
https://www.ncbi.nlm.nih.gov/pubmed/31207916
http://dx.doi.org/10.3390/ijms20122913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628582/
https://www.ncbi.nlm.nih.gov/pubmed/31207916
http://dx.doi.org/10.3390/ijms20122913

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